Action potential–independent spontaneous microdomain Ca2+ transients–mediated continuous neurotransmission regulates hyperalgesia

Proceedings of the National Academy of Sciences, Volume 122, Issue 3, January 2025.
SignificanceThe neurotransmission between dorsal root ganglion (DRG) and spinal cord neurons is essential for pain sensation. Mounting evidence has established the crucial roles of action potential (AP)-evoked neurotransmission from DRG neurons in chronic …
Source : National Academy of Sciences