Activation of the proton-sensing GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory joint pain

Proceedings of the National Academy of Sciences, Volume 121, Issue 51, December 2024.
SignificanceThe lack of effective and safe drugs for pain management in chronic inflammatory conditions represents a significant unmet clinical need. Consequently, enhanced understanding of pain mechanisms is required to support novel analgesic …
Source : National Academy of Sciences