Assembly-enhanced recognition: A biomimetic pathway to achieve ultrahigh affinities

Proceedings of the National Academy of Sciences, Volume 122, Issue 3, January 2025.
SignificanceHigh-affinity molecular recognition has carried the mysteries of life processes and serves as the foundation for the biomedical applications of macrocyclic receptors. Achieving the ultrahigh affinity binding of macrocyclic hosts remains a …
Source : National Academy of Sciences