Distinct modulation of calcium-activated chloride channel TMEM16A by drug-binding sites

Proceedings of the National Academy of Sciences, Volume 121, Issue 51, December 2024.
SignificanceTMEM16A is a calcium-activated chloride channel critical for normal physiology, including blood vessel function and fluid transport in the body. It has emerged as a promising target for treating diseases like hypertension, stroke…
Source : National Academy of Sciences