Enhancing drug solubility through competitive adsorption on silica nanosurfaces with ultrahigh silanol densities

Proceedings of the National Academy of Sciences, Volume 122, Issue 4, January 2025.
SignificanceAccording to the statistics in the pharmaceutical industry, over 60% to 70% of drug candidates in the pipeline suffer from low solubility, a factor that significantly hampers their chances of passing clinical tests and being commercialized…
Source : National Academy of Sciences