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HomeScience and NatureKDM5D histone demethylase mediates p38α inactivation via its enzymatic activity to inhibit cancer progression

KDM5D histone demethylase mediates p38α inactivation via its enzymatic activity to inhibit cancer progression

by News7

Proceedings of the National Academy of Sciences, Volume 121, Issue 50, December 2024.
SignificanceThe dysregulation of the p38α MAPK pathway is often linked to abnormal cell inflammation, death, and proliferation, contributing to tumorigenesis. Posttranslational modifications (PTMs) play a pivotal role in regulating p38α activation, yet …
Source : National Academy of Sciences

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