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HomeScience and NatureLarge-scale CRISPR/Cas9 deletions within the WFDC gene cluster uncover gene functionality and critical roles in mammalian reproduction

Large-scale CRISPR/Cas9 deletions within the WFDC gene cluster uncover gene functionality and critical roles in mammalian reproduction

by News7

Proceedings of the National Academy of Sciences, Volume 121, Issue 51, December 2024.
SignificanceThis study fundamentally advances our understanding of male reproductive biology by elucidating the essential roles of the telomeric whey acidic protein four-disulfide core (WFDC) gene cluster in spermatogenesis and sperm function. Using a …
Source : National Academy of Sciences

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