Permanent cilia loss during cerebellar granule cell neurogenesis involves withdrawal of cilia maintenance and centriole capping

Proceedings of the National Academy of Sciences, Volume 121, Issue 52, December 2024.
SignificanceSonic hedgehog (SHH) promotes proliferation of granule cell (GC) progenitors in the postnatal cerebellum and in the pediatric tumor, medulloblastoma, through specialized compartments called primary cilia. During neuronal maturation, GCs stop …
Source : National Academy of Sciences