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HomeScience and NatureSequence complexity and monomer rigidity control the morphologies and aging dynamics of protein aggregates

Sequence complexity and monomer rigidity control the morphologies and aging dynamics of protein aggregates

by News7

Proceedings of the National Academy of Sciences, Volume 121, Issue 50, December 2024.
SignificanceProtein aggregates exhibit diverse morphology, exemplified by amyloid fibrils, gel-like structures, and liquid-like condensates. Differences in the morphologies in identical proteins play important functional roles in several diseases. …
Source : National Academy of Sciences

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