SKA2 enhances stress-related glucocorticoid receptor signaling through FKBP4–FKBP5 interactions in neurons

Proceedings of the National Academy of Sciences, Volume 121, Issue 52, December 2024.
SignificanceOur study uncovers a role for the cell cycle gene SKA2 in the regulation of stress-related signaling in the brain, specifically its involvement in the glucocorticoid receptor (GR) pathway and hypothalamic–pituitary–adrenal (HPA) axis function…
Source : National Academy of Sciences