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HomeScience and NatureSpecific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes | Science

Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes | Science

by News7

The CCR4-NOT complex is a major regulator of eukaryotic messenger RNA (mRNA) stability. Slow decoding during translation promotes association of CCR4-NOT with ribosomes, accelerating mRNA degradation. We applied selective ribosome profiling to further …
Source : ScienceMag

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