The LIM-domain-only protein LMO2 and its binding partner LDB1 are differentially required for class switch recombination

Proceedings of the National Academy of Sciences, Volume 122, Issue 4, January 2025.
SignificanceClass switch recombination (CSR) diversifies the effector functions of antibodies to fight antigens. CSR involves complex regulations of DNA double-strand break (DSB) repair and transcriptional control with mechanisms not completely …
Source : National Academy of Sciences